I realize that we barely have any info thus far concerning the story. But 343i have said this will be a good place for new players to start and not feel lost. Seems to me trying catch them up on the events of 4 and 5 would take a lot to do in an opening cinematic. Possibly the Infinity all the characters associated with it may be absent in the game with no explanation. Hoping I’m wrong, but if their goal is to tell simpler stories then I don’t see how you can fit the Infinity or even the Spirit of Fire into Infinite’s story.
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Infinity Possibly Gone